PHYSOSTIGMA VENENOSUM

PHYSOSTIGMA VENENOSUM
Calabar Bean

This remedy and its active principle, Eserine, form a valuable addition to Materia Medica. Stimulates heart, raises blood pressure, and increases peristalsis. Causes contraction of the pupil and of the ciliary muscles. Induces a condition of short-sightedness. Spinal irritation, loss of motility, prostration, with very sensitive vertebræ Fibrillary tremors. Rigidity of muscles; paralysis. Depresses the motor and reflex activity of the cord and causes loss of sensibility to pain, muscular weakness, followed by complete paralysis, although muscular contractility is not impaired. Paralysis and tremors, chorea. Meningeal irritation, with rigidity of muscles. Tetanus and trismus. Polymyelitis anterior. Eserine is used locally to produce contraction of pupil.

Head.–Constant pain on top; vertigo, with constrictive feeling of head. Pain over orbits; cannot bear to raise eyelids. Cerebro-spinal meningitis; general tetanic rigidity. Spastic conditions of the face-muscles.

Eyes.–Night-blindness (Opposite: Bothrops); photophobia; contraction of pupils; twitching of ocular muscles. Lagophthalmus. Muscæ volitantes; flashes of light; partial blindness. Glaucoma; paresis of accommodation; astigmatism. Profuse lachrymation. Spasm of ciliary muscles, with irritability after using eyes. Increasing myopia. Post-diphtheritic paralysis of eye and accommodation muscles.

Nose.–Fluent coryza; burning and tingling of nostrils; nose stuffed and hot. Fever-blisters around nostrils.

Mouth.–Tongue feels sore on tip. Feeling as if a ball came up throat.

Throat.–Strong heart-pulsation felt in throat.

Stomach.–Great pain immediately after eating. Sensitive to pressure in epigastric region. Pain extends into chest and down arms. Gastralgia; chronic constipation.

Female.–Irregular menstruation, with palpitation. Congestion of eyes. Rigid muscles.

Heart.–Feeble pulse; palpitation; spasmodic action, with feeling pulsation through the whole body. Beats of heart distinctly perceptible in chest and head. Fluttering of heart felt in throat. Fatty degeneration (Cup ac).

Extremities.–Pain in right popliteal space. Burning and tingling in spine. Hands and feet numb. Sudden jerking of limbs on going to sleep. Tetanic convulsions. Locomotor ataxia. Numbness in paralyzed parts, crampy pains in limbs.

Relationship.–Compare: Eserine-the alkaloid of Physostigma–(slows action of heart and increases arterial tension; in ciliary spasm and spasmodic astigmatism due to irregular action of ciliary muscles; blepharo-spasms; pupils contracted. Twitching of lids, soreness of eyeballs, blurring of vision after using eyes, pains around eyes and head). Used locally to contract the pupil. Eserine contracts the pupils dilated by Atropin, but not those dilated by Gelsemium. Internally 6x.

Eserin Salicylate (post-operative intestinal paralysis; meteorism. Hypodermically 1/60-1/40 gr).

Compare also: Muscarin; Conium; Curare; Gels; Thebainum (tetanus); Piperazinum–(Uric acid conditions. Pruritus. Gout and urinary calculi. Constant backache. Skin dry, urine scanty. Rheumatic urthritis. Give one grain daily in carbonated water. First and second decimal trituration three times a day).

Antidote: Atropia. In full medicinal doses will relieve most of the effects of physostigmine.

Dose.–Third potency. The neutral sulphate of Eserine is instilled into the eye, from one-half to four grains to one ounce distilled water, to induce contraction of pupil, in mydriasis, injuries to the eye, iritis, corneal ulcers, etc.


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Homeopathy studies the whole person. Characteristics such as your temperament, personality, emotional and physical responses etc. are of utmost importance when prescribing a remedy. Thus please give as much information as possible and answer as many of the questions as you can. The answer boxes will scroll to meet your needs. You can ask for professional advice on any health-related and medical subject. Medicines could be bought from our Online Store or Homeopathic store near you.

Homeopathy is a system of alternative medicine that is based on the concept of “like cures like.” It uses highly diluted substances that are believed to cause similar symptoms as the illness being treated.

There are many online homeopathic Materia medica, which are resources that list and describe the properties and uses of different homeopathic remedies. Some popular online homeopathic Materia medica include:

Boericke’s Materia Medica: A comprehensive reference guide to homeopathic remedies, including information on their uses, indications, and dosages.

Clarke’s Dictionary of Homeopathic Materia Medica: A well-respected and widely used reference that includes information on the symptoms that each remedy is used to treat.

Homeopathic Materia Medica by William Boer Icke: A popular homeopathic reference book that provides in-depth information on a wide range of remedies, including their indications, symptoms, and uses.

The Complete Repertory by Roger van Zandvoort: A comprehensive online reference that provides information on remedies, symptoms, and indications, and allows users to search for remedies based on specific symptoms.

There are many writers who have contributed to the development of homeopathic materia medica. Some of the most well-known include:

Samuel Hahnemann: The founder of homeopathy, Hahnemann wrote extensively about the use of highly diluted substances in the treatment of illness. He is best known for his work “Organon of the Medical Art,” which outlines the principles of homeopathy.

James Tyler Kent: Kent was an American homeopathic physician who is known for his contributions to homeopathic materia medica. He wrote “Repertory of the Homeopathic Materia Medica,” which is still widely used today.

William Boericke: Boericke was an Austrian-American homeopathic physician who wrote “Pocket Manual of Homeopathic Materia Medica.” This book is considered one of the most comprehensive and widely used homeopathic reference books.

George Vithoulkas: Vithoulkas is a Greek homeopathic physician and teacher who has written several books on homeopathic materia medica, including “The Science of Homeopathy” and “Essence of Materia Medica.”

Robin Murphy: Murphy is an American homeopathic physician who has written several books on homeopathic materia medica, including “Homeopathic Clinical Repertory” and “Homeopathic Medical Repertory.”

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