Eserine. Physostigmine. The alkaloid of Physostigma venenosum, Calabar Bean. C15 H21 N3 O2. Trituration or solution.


Clinical.-Blepharospasm. Ciliary spasm. Glaucoma. Headache. Pupil, contracted. Salivation. Sweat, excessive.


Characteristics.-Eserine is best known as used by oculists to procure contraction of the pupils in glaucoma. It has been used by Fenoch of Berlin (H. R., iv. 127) in a case of chorea in a child of nine. Half a millegramme of Eser. sulph. was injected into the right upper arm, and the following proving was the result: In fifteen minutes the child cried out loudly, vomited profusely, and complained of violent headache. Soon the face and upper part of the body became covered with profuse sweat. Half an hour later the flow of saliva was increased. The heart-beats sank to 64, radial artery contracted, pulse small and thready. After repeated vomitings signs of cardiac weakness increased in spite of remedies, whilst sweat and saliva decreased, and in one half-hour had disappeared. A moderate contraction of the pupil took place, reaction slow. The child lay apathetic on the bed, pale and collapsed. Antidotes were administered, and the child was well next morning. A remark of Mittendorf that “spasm of the accommodation is also produced artificially by Eserin.” led R. B. Leach (Med. Adv., xix. 262) to prescribe successfully the 6x trituration in cases of ciliary spasm, and of astigmatism due to irregular action of the ciliary muscles. Eserin. has also produced blepharospasm. A solution of one grain to the drachm (mixed in mistake for a grain to the ounce) was instilled into the eye of a lady of 60 suffering from cataract. Sweating and lachrymation followed, and, as these passed off, in a quarter of an hour “clonic spasm of the eyelids” set in, “the upper lid failing down on the lower every few seconds.” Spasmodic feeling in lips and the same sensation under jaw of left side followed. Feeling of tremor and spasm, without retinal movement, followed in an hour. Pupils contracted to small point.


Relations.-Compare: Physostigma, Pilocarpine.




1. Mind.-Child cried out loudly.-Apathetic.


2. Head.-Violent headache with repeated vomiting.


3. Eyes.-Moderate contraction of pupils; reaction slow, by shading the eyes they did not enlarge; on exposure to strong light they contracted slightly, but returned to their normal size.-Spasm of accommodation; ciliary spasm.-Pain and irritation of eyes on continued reading.-Blepharospasm.


6. Face.-Face pale.


8. Mouth.-Saliva, first increased, later arrested.


11. Stomach.-Vomited profusely and complained of headache.-Repeated vomiting with signs of cardiac weakness.


19. Heart.-After repeated vomiting signs of cardiac weakness increased.-Heart-beats sank to 64; radial artery contracted; pulse small and thready.


24. Generalities.-The child lay apathetic on the bed, pale and collapsed.


27. Fever.-Face and upper part of the body covered with profuse perspiration.

“Materia Medica” is a term commonly used in the field of homeopathy to refer to a comprehensive collection of information on the characteristics and therapeutic uses of various natural substances, including plants, minerals, and animal products.

One such work is “Materia Medica,” a book written by Benoit Mure, a French homeopath, in the 19th century. The book is considered a valuable resource for homeopaths and is still widely used today.

In “Materia Medica,” Mure provides detailed information on over 100 homeopathic remedies, including their sources, preparation methods, physical and mental symptoms, and indications for use. He also discusses the philosophy and principles of homeopathy, as well as its history and development.

The book is known for its clear and concise writing style, and it has been praised for its accuracy and depth of knowledge. It remains a popular reference for homeopaths and students of homeopathy.

Overall, “Materia Medica” by Benoit Mure is an important work in the field of homeopathy and is highly recommended for anyone interested in learning about the use of natural remedies in the treatment of various health conditions.

Online Materia Medica 

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Homoeopathy studies the whole person. Characteristics such as your temperament, personality, emotional and physical responses etc. are of utmost importance when prescribing a remedy. Thus please give as much information as possible and answer as many questions as possible. The answer boxes will scroll to meet your needs. You can ask for professional advice on any health-related and medical subject. Medicines could be bought from our Online Store or Homeopathic store near you.

Homoeopathy is a system of alternative medicine that is based on the concept of “like cures like.” It uses highly diluted substances that are believed to cause similar symptoms as the illness being treated.

There are many online homoeopathic Materia medica, which are resources that list and describe the properties and uses of different homoeopathic remedies. Some popular online homoeopathic Materia medica include:

Boericke’s Materia Medica: A comprehensive reference guide to homoeopathic remedies, including information on their uses, indications, and dosages.

Clarke’s Dictionary of Homeopathic Materia Medica: A well-respected and widely used reference that includes information on the symptoms that each remedy is used to treat.

Homeopathic Materia Medica by William Boer Icke: A popular homoeopathic reference book that provides in-depth information on a wide range of remedies, including their indications, symptoms, and uses.

The Complete Repertory by Roger van Zandvoort: A comprehensive online reference that provides information on remedies, symptoms, and indications, and allows users to search for treatments based on specific symptoms.

There are many writers who have contributed to the development of homoeopathic materia medica. Some of the most well-known include:

Samuel Hahnemann: The founder of homoeopathy, Hahnemann wrote extensively about the use of highly diluted substances in treating illness. He is best known for his work “Organon of the Medical Art,” which outlines the principles of homoeopathy.

James Tyler Kent: Kent was an American homoeopathic physician who is known for his contributions to homoeopathic materia medica. He wrote “Repertory of the Homeopathic Materia Medica,” which is still widely used today.

William Boericke: Boericke was an Austrian-American homoeopathic physician who wrote the “Pocket Manual of Homeopathic Materia Medica.” This book is considered one of the most comprehensive and widely used homoeopathic reference books.

George Vithoulkas: Vithoulkas is a Greek homoeopathic physician and teacher who has written several books on homoeopathic materia medica, including “The Science of Homeopathy” and “Essence of Materia Medica.”

Robin Murphy: Murphy is an American homoeopathic physician who has written several books on homoeopathic materia medica, including “Homeopathic Clinical Repertory” and “Homeopathic Medical Repertory.”


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